The U.S. government, particularly the executive branch and its negotiators, would be directly affected as this resolution expresses the strong preference of a segment of the Senate regarding future diplomatic efforts with Iran. While not legally binding, it signals congressional sentiment and could influence how negotiators approach talks.

The Iranian government would also be affected, as the resolution outlines very stringent conditions that the U.S. Senate believes Iran must meet for any nuclear deal to be considered acceptable. It communicates a non-negotiable baseline from this group of Senators. Countries involved in international diplomacy concerning Iran's nuclear program would also take note of this declared U.S. Senate position.