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Chronic Traumatic Encephalopathy (CTE)

A progressive degenerative brain disease found in people with a history of repeated head injuries, which can lead to problems with memory, judgment, mood, and behavior.

Repeated Head Impacts (RHI)

Multiple blows to the head, often subconcussive (meaning they don't always cause immediate concussion symptoms), that can lead to long-term brain damage.

Tau Protein

An abnormal protein that builds up in the brains of people with CTE and other neurodegenerative diseases like Alzheimer's, leading to brain cell damage.

Neurodegenerative Disease

A condition characterized by the progressive loss of structure or function of neurons, which are basic units of the nervous system, leading to conditions like dementia or Parkinson's.

Postmortem Neuropathological Analysis

The medical examination of brain tissue after death to diagnose diseases like CTE by looking at changes in the brain's structure and cells.

Subconcussive Blows

Hits to the head that are not strong enough to cause a diagnosed concussion but can still contribute to brain damage over time, especially when repeated.