The individuals most directly affected would be families and caregivers of premature infants, especially those who have experienced Necrotizing Enterocolitis (NEC) or are at risk of it. This includes parents whose babies are born prematurely or with medical complications that make them vulnerable to NEC. Medical professionals, particularly those working in neonatal intensive care units (NICUs) and pediatric research, would also be affected as the awareness day encourages better practices and research into prevention and treatment.

The general public, especially those who may not be aware of NEC, would be indirectly affected by the increased information and educational efforts surrounding the awareness day. Ultimately, this increased awareness could lead to better support systems for affected families and potentially more funding and focus on research to combat this severe condition.