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Controlled Substances Act (CSA)

A federal law that regulates the manufacture, importation, possession, use, and distribution of certain drugs and substances in the United States.

Schedule I

The most restrictive category under the Controlled Substances Act, reserved for drugs with a high potential for abuse, no currently accepted medical use in treatment, and a lack of accepted safety for use under medical supervision.

7-hydroxymitragynine (7-OH)

A chemical compound found naturally in the kratom plant, which can also be produced synthetically in a laboratory, and is known to have opioid-like effects.

Mitragyna speciosa Korth (kratom)

A tropical tree native to Southeast Asia, whose leaves are traditionally used for their stimulant and opioid-like properties.

Synthetic equivalents

Lab-made versions of a chemical substance that have the same structure and effects as the original, rather than being derived directly from a natural source.